2 Minute Medicine2h
AAV9.LAMP2B gene therapy shows clinical benefit in Danon disease
In seven patients with Danon disease, a single infusion of adeno-associated virus serotype 9 carrying transgene LAMP2B ...
2 Minute Medicine7h
Serum glial fibrillary acidic protein levels may be helpful to aid diagnosis of sports related head injuries
Glial fibrillary acidic protein (GFAP) levels peak around 24 hours after traumatic brain injury (TBI) 2. Higher GFAP levels ...
2 Minute Medicine5h
Male partner treatment lowers the risk of bacterial vaginosis reoccurrence
In this randomized controlled trial, female patients with bacterial vaginosis (BV) had lower recurrence rates when their male ...
2 Minute Medicine23h
Hypnotic drug use may be associated with increased risk of postoperative delirium
Older age, hypnotic drug use, and higher intraoperative fluid load were independent risk factors associated with postoperative delirium development after pancreatic surgery. Evidence Rating Level: 2 ...
2 Minute Medicine1d
Remibrutinib alleviates symptoms in chronic spontaneous urticaria resistant to H1-antihistamines
In this randomized controlled trial, among patients with chronic spontaneous urticaria who continue to have symptoms while on ...
2 Minute Medicine1d
Low-dose yellow fever vaccine non-inferior to standard dose
This randomized controlled trial conducted in Kenya and Uganda assessed whether fractional doses of the 17D-204 yellow fever ...
2 Minute Medicine1d
Durvalumab and bevacizumab plus chemoembolization improves progression-free survival in hepatocellular carcinoma
Progression-free survival was significantly greater in the durvalumab plus bevacizumab group compared to placebo. 2. Common treatment-related adverse events included hypertension and anemia. Evidence ...
2 Minute Medicine2d
Recognition of kidney allograft microvascular inflammation refines risk stratification for allograft outcomes
Patients with a nonrejection-related diagnosis according to the 2019 Banff classification who were reclassified as MVI, ...
2 Minute Medicine2d
Coronary CT-angiography-guided management improves outcomes in patients with stable chest pain
Composite of coronary heart disease death and non-fatal myocardial infarction was less frequent in the CCTA group compared to ...
2 Minute Medicine8d
Plozasiran reduces triglyceride levels and acute pancreatitis incidence in persistent chylomicronemia
In this randomized controlled trial, among patients with persistent chylomicronemia, it was found that plozasiran more ...
2 Minute Medicine7d
Mpox cases in Africa continued to increase following WHO emergency declarations
The number of mpox cases in Africa increased leading up to the first mpox declaration of a Public Health Emergency of ...
2 Minute Medicine3d
Endometriosis and Uterine Fibroids Associated with a Greater Risk of Mortality due to Gynecologic Cancers
A history of endometriosis and uterine fibroids in women was associated with a greater risk of premature mortality and mortality due to gynecological cancers. 2. A history of endometriosis in women ...