USA Today's NFL experts make their picks for a Week 3 showdown between the San Francisco 49ers and Arizona Cardinals

Arizona Cardinals vs Carolina Panthers picks, predictions, odds, win probabilities for NFL Week 2 Sunday game on Sept. 14, 2025. Who will win game?

Wide receiver Tetairoa McMillan and running back Jacory Croskey-Merritt represented the Arizona Wildcats well with successful NFL debuts.

College football is headed to London, England. Arizona State and Kansas are in discussions to meet in Wembley Stadium on Sept. 16, 2026 in the first installment of what's expected to be a multi-year event called the Union Jack Classic, according to a report from The Post and Courier .

What TV channel is Arizona Cardinals vs San Francisco 49ers game on? Time, how to watch on television, how to stream NFL Week 3 game Sunday, Sept. 21.

Arizona Cardinals star quarterback Kyler Murray has apologized after posting an unfortunate photo on Instagram earlier this week. Murray posted a photo of himself in a Michael Vick Virginia Tech jersey on his page. He was accompanied in the picture by his pit bull, Trunks. You can check out the photo, which has since been deleted, here.

"Justin Jefferson is 26 years and 90 days old today, and with his first catch tonight vs. the Falcons, he’ll tie Larry Fitzgerald as the youngest player in NFL history to reach 500 career receptions. Fitzgerald also was exactly 26 years and 90 days old in 2009 when he caught his 500th NFL pass."

Former Arizona State star Cam Skattebo led the Giants in rushing with 45 yards on 11 carries against the Dallas Cowboys.