New hifiasm-ONT assembly method delivers high-quality, cost-efficient near T2T assemblies using standard Oxford Nanopore Simplex reads, broadening access to comprehensive genome assemblies across ...

Provided the constraints are linear, problems of this kind are normally forced into a linear programming mould and solved using the simplex method. This paper takes another look at the associated ...

In this paper, a modification of the bisection simplex method is made for more general purpose use. Organized in an alternative simpler form, the modified version exploits information of the optimal ...

OXFORD, England, April 18, 2025--A new paper, released this week on bioRxiv, introduces hifiasm-ONT, a breakthrough genome assembly algorithm that enables partially phased, near telomere-to-telomere ...