"We need to continue learning more about the different versions of reverse transcriptase at work in the aging and especially Alzheimer's disease brain," added Chun.

Use of nucleoside reverse transcriptase inhibitors (NRTIs) is associated with a significantly lower risk of developing Alzheimer disease (AD), according to findings published in Alzheimer’s & Dementia ...

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, Tracy Diamond and colleagues from Merck & Co., Inc., Rahway, NJ, ...

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) comprise approximately 10% of the HIV drug market worldwide, and efavirenz leads this class with $680 million annual sales in the United ...

Clinicians typically classify meningiomas—the most common type of brain tumor—into three grades, ranging from slow-growing to ...

New England Biolabs (NEB®) announced today that they have released a novel, thermostable reverse transcriptase, WarmStart® RTx Reverse Transcriptase, specifically designed for nucleic acid detection.

Clin Drug Invest. 2007;27(8):509-531. Antiretroviral drugs (ARVs) can be divided into four different classes according to their modes of action: nucleoside or nucleotide reverse transcriptase ...

Merck’s once-monthly oral HIV prevention pill, MK-8527, advances to Phase III and may offer an accessible PrEP option in the future.

In this issue of hLife, the team led by Prof. Min Wang from Ocean University of China systematically mined and characterized the diversity of viral reverse transcriptases from global metagenomic ...

“Most efforts are along the lines of silencing its activity,” Holt says. One promising approach involves repurposing reverse ...

HIV-1 reverse transcriptase inhibitors remain a cornerstone of antiretroviral therapy, targeting the enzyme responsible for converting viral RNA into DNA. This class of drugs, particularly ...

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, ...