The San Francisco Giants (19-10) and the San Diego Padres (17-11) open a 2-game set Tuesday at Petco Park. First pitch is scheduled for 9:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Giants vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Nathan Eovaldi claimed the win over the Giants on Friday and combined with the bullpen to shut San Francisco out. Saturday’s starter, Tyler Mahle, took a no-decision but the Giants only scored three runs. On Sunday, Jack Leiter returned and he struggled with walks, but he didn’t allow the game to get away from him.

Preview the April 27 matchup between the San Francisco Giants and Texas Rangers with odds over/under, game spread, betting lines and more.