With Deebo Samuel in Washington and Brandon Aiyuk not expected to play until Week 6, the San Francisco 49ers’ wide

Head coach Kyle Shanahan helped lead the San Francisco 49ers to the NFC Conference Championship (plus one Super Bowl) for

More than 10 years after two people were shot dead in separate locations in San Francisco, police announced on Tuesday an arrest in the cold case.

San Francisco quarterback Mac Jones sustained a knee sprain in the 49ers’ second preseason game on Saturday and won’t be available when the NFL team closes its preseason schedule on Saturday.

City officials point to cleaner streets as evidence that a more active approach is working. Some say the tactics are making conditions worse.

An early morning fire at a Sunset District home spread to neighboring houses on Wednesday, injuring three people and killing a pet cat, authorities said.

Leaping AI cofounder Kevin Wu said the startup struggled to get funding in Germany but that it was easy after Y Combinator and moving to the US.

The company Brownstone Shared Housing, which rents out tiny sleeping pods inside an old San Francisco bank, is accused of falling behind on rent.

Downtown Oakland’s office vacancy rate was 37.2% in the second quarter, up from 34.9% in the first quarter. San Francisco’s vacancy rate was 34.8% in the second quarter, slightly higher than the 34.7% rate in the first quarter.

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