"jay leno is a mean a--hole #biggestloserdocumentary," O'Donnell wrote in the caption of her post, which featured screenshots from both the docuseries and "The Tonight Show."

Carla Triplett made The Biggest Loser history when she appeared on the show’s seventh season in 2009 at 379 pounds — the heaviest for a contestant at the time.

One of the shocking stories has included a contestant revealing that the physical training she underwent on her first day filming led to her waking up in the hospital and realizing “I knew I died that...