Jeremy Peña and Christian Walker each hit a three-run homer, and the Houston Astros outslugged the Baltimore Orioles 10-7

McCullers is set to rejoin the rotation Friday in Baltimore after missing more than a month of action with a blister on his pitching hand. The veteran right-hander threw 80 pitches and went five innings in his lone rehab start, so he shouldn't have much of a workload restriction Friday.

Bennett Sousa, who had elevated to a high-leverage role in Josh Hader's absence, is sidelined with what has been called elbow inflammation.